acetaminophen napqi glutathione alcohol - MSK Problem 2: N-acetyl para-benzoquinone (NAPQI)
Problem 2: N acetyl para benzoquinone (NAPQI) is an oxidized What happens when you take paracetamol? Your liver gets to work breaking it down into harmless bits. But here's the twist Those bits need a taxi (yep, a molecule called glutathione) Acetaminophen (Paracetamol) Toxicity A common and potentially fatal cause of acute liver failure due to toxic accumulation of the metabolite NAPQI when glutathione stores are depleted. Early recognition and timely administration Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram
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