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307 The ER regulates the expression of unfolded protein response (UPR)-related target genes by increasing the formation of transcription factors ATF4, XBP1, and ATP6, providing cellular stress tolerance

Limited glucose intake redirects the body towards the utilization of ketone bodies, resulting in beneficial effects in cancer treatment with the ketogenic diet

Sexually dimorphic factors linking OS with AD development and progression also include the levels of glutathione, alteration of mitochondria, and the levels of metal ions in the brain (254, 255, 260, 270)

Secondary aims are to explore the mechanisms through which exercise may prove beneficial, and to explore the key considerations in designing future clinical trials in which the potential of exercise to promote recovery from an episode of AKI can be tested