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This is described as the effect that long-term or chronic use of stimulants causes, resulting in a worsening of symptoms over time

2001;354(Pt 2):23342

3.3 Chemical carrier function Microplastic particles demonstrate significant capacity to function as vectors for neurotoxic environmental contaminants, effectively concentrating and transporting these compounds to neuronal populations that would otherwise experience limited exposure

There has been considerable evidence of NMs protecting crops, enhancing the yield, and alleviating the adverse effects of pesticides and fertilizers on cereal crops, fruit, and vegetable crops (Parra-Torrejn et al., 2023