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When interpreted together with the findings of the STEP 4 withdrawal trial and STEP 1 off-treatment extension study, which both showed weight regain after semaglutide discontinuation (after 20 weeks treatment in STEP 4 and 68 weeks treatment in STEP 1) 23,24 , these results support the benefit of continued semaglutide treatment for sustained weight loss

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Results: We identified peptides from wheat, Saccharomyces cerevisiae , microbiota, tobacco, and pathogens that activated both the V3S1/V13S1 TCR and CD8 + T cells from psoriasis patients