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The most common causes of degradation include: Heat exposure Moisture contamination UV light Oxidation Freeze-thaw cycles Bacterial contamination after reconstitution Improper storage may affect peptide stability and reduce consistency in laboratory analysis

Dysfunctional EPCs are involved in the pathogenesis of CVD [80]

Metabolic changes included a reduction of the usage of muscle glycogen (i.e., its carbohydrate stores) during low-intensity exercise (consistent with an increase in lipid utilization) and streamlined glucose metabolism and mitochondrial flux during high-intensity exercise, leading to reduced anaerobic ATP production (which is what leads to lactic acid build-up in muscles)