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Suspension products must be shaken thoroughly before use to ensure a consistent concentration

Results: 760 patients were included, mean age was 73 (SD 7) years and 520 (68%) were men

These effectors catalyze protein ubiquitination by a mechanism involving the production of ADP-ribosylated ubiquitin (ADPR-Ub) as the reaction intermediate using their monoADP-ribosyltransferase (mART) activity 6

Maintenance Treatment Following First-line Pemetrexed Plus Platinum Chemotherapy The efficacy of pemetrexed as maintenance therapy following first-line platinum-based chemotherapy was also evaluated in PARAMOUNT (NCT00789373), a multi-center, randomized (2:1), double-blind, placebo-controlled study conducted in patients with Stage IIIb/IV non-squamous NSCLC who had completed four cycles of pemetrexed in combination with cisplatin and achieved a complete response (CR) or partial response (PR) or stable disease (SD)