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For context on how age-related changes affect peptide function, the discussion of longevity peptides provides useful background

Levels in the body decline significantly with age from around 200 ng/mL at age 20 to under 80 ng/mL by age 60. In cosmetic research, GHK-Cu is associated with collagen and elastin synthesis, antioxidant activity, and overall skin renewal processes

Despite Dihexas structural derivation from Ang IV, mechanistic studies have established that the compound does not act through the classical AT 4 receptor (insulin-regulated aminopeptidase, IRAP)

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