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Subjects were seen at 6 months intervals after enrollment

Plant Mol

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Li et al., in vivo data, chlorpyrifos (CPF), an OP insecticide associated with cognitive impairment, oxidative stress and neuronal damage caused a significant increase in A levels in the cortex and hippocampus, as well as increased memory loss and reduced motor activity in Tg2576 mice 6 months after an acute subcutaneous administration of 50 mg/Kg of CPF (Salazar et al., 2011)