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doi: 10.1016/j.pbi.2004.09.014 [DOI] [PubMed] [Google Scholar] 23.Woollard AAD, Moore I

Steroids are only indicated in the moderate to severe cases of IBD

Read the poster here: Using the genO-hSA/hFcRn model to test four clinically approved ADCs (TDXd, TDM1, SG, EV), they showed: - genO-hSA/hFcRn mice generate ADC halflives that closely match human clinical data - The genO-hSA/hFcRn mice outperformed other hFcRn mouse models and WT mice, which consistently overestimate exposure