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This study successfully identified C5 and SCP2 as promising drug targets through Mendelian randomization and Bayesian colocalization, and highlighted beta-Amyrone as a potential dual-target inhibitor with strong binding affinity to both proteins, paving the way for innovative treatment strategies

-20C, 1 month (protect from light) Biological Activity apoptosis and inflammatory responses by up-regulating the expression level of ER , thereby improving cognitive function in Alzheimer's disease models

Although inexpensive and easy to carry out, this method is only able to detect cases with 20% or less of mean normal G6PD activity and misses most of the moderate G6PD activity especially in female heterozygotes (4)