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Age-related Huntingtons disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

The procedure is relatively quick, often taking less than an hour, and usually requires multiple sessions spaced a few weeks apart for best results

Furthermore, all reactions were carried out based on the following cycle parameters: kept at 95C for 10 min, then followed by 40 cycles of 95C for 15 s and 60C for 45 s