Although peripheral and central enterostatin administration decreases dietary fat intake in animals (while enterostatin-receptor antagonists did the opposite) (186), its administration to humans has shown no effects on food intake, appetite, energy expenditure, or body weight (187)
Glutamate biosynthesis is not only important for production of glutamate
Abbreviations AD : Alzheimer disease ALS : Amyotrophic lateral sclerosis Aps : Spontaneous action potentials CA1 : Cornu ammonis 1 CA3 : Cornu ammonis 3 CCK-8 : Cell counting Kit-8 assay ChIP : Chromatin immunoprecipitation assay CKO : Conditional knockout DCFH-DA : Fluorescent probe 2,7-Dichlorodi-hydrofluorescein diacetate DEGs : Differentially expressed genes DFX : Deferoxamine DG : Dentate gyrus EEG : Electroencephalogram recordings ELISA : Enzyme-linked immunosorbent assay GFAP : Glial fibrillary acidic protein GSDMD : Gasdermin D IC : 50 The half maximal inhibitory concentration LPS : Lipopolysaccharide MMP : Mitochondrial membrane potential N2a : The mouse neuroblastoma neuro-2a cells NeuN : Neuronal nuclei NLRP3 : NOD-like receptor family pyrin domain containing 3 OCT : Optimum cutting temperature compound PD : Parkinson's disease PILO : Pilocarpine p-STAT3 : Phosphorylated signal transducer and activator of transcription 3 PTZ : Pentylenetetrazole pY 705 -STAT3 : STAT3 Tyr705 phosphorylation qRT-PCR : Real-time quantitative reverse transcription PCR ROS : Reactive oxygen species SE : Status epilepticus siRNA : Small interfering RNA STAT3 : Signal transducer and activator of transcription 3 TLC : Thin-layer chromatography TPEN : The membrane-permeable Zn 2+ chelator TRM : Tremor rat TRPM7 : Transient receptor potential melastatin 7 TRPM7-CKO : TRPM7 conditional knockout TSQ : The N-(6-methoxy-8-quinolyl)-para-toluenesulfonamide TTM : Tetrathiomolybdate SK : Small conductance Ca 2+ -activated K + References Shi J, Gao W, Shao F
PubMed Wessells H, Gralnek D, Dorr R, Hruby VJ, Hadley ME, Levine N (2000)
