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The inhibition of PKC by T may be an important factor, since platelet aggregation induced by the PKC activator PMA was reduced by vitamin E in most studies concomitantly with a reduction in PKC activity ( Reference Freedman, Farhat and Loscalzo 67 Reference Liu, Wallmon and Olsson-Mortlock 69 )

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It can accumulate in the brain and adrenal glands (10 mM), where there are the highest concentrations of VIC, while in the muscle and myocardium, concentrations are lower (0.2 mM)

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