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In PD models, oral administration of Curli-producing bacteria enhanced -syn aggregation and motor deficits in mice, whereas germ-free or antibiotic-treated mice had less -syn pathology [91, 92]

The Rising Tide of dementia in Canada: What does it mean for pharmacists and the people they care for

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This review provides an overview of gut microbiota on inflammation and oxidative stress in renal fibrosis, briefly discusses regulation of the gut flora using microecological preparations and natural products, such as resveratrol, curcumin and emodin as treatments for CKD, and provides a clear pathophysiological rationale for the design of promising therapeutic strategies