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Additionally, 14 healthy adult participants did not exhibit any association between their serum vitamin B12 levels and actigraphy-assessed sleep parameters before and two weeks after receiving 3 mg/day cyanocobalamin supplementation [42]

Science 314:14611463

TABLE 2 The regression equation, linear range, r 2 , and LLOQ of six analytes in plasma and brain tissue (n = 6)

Since excessive vascular ROS generation is the key driver of endothelial dysfunction and the main trigger of eNOS uncoupling, attempts have been made to mitigate oxidative stress