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Investigation of MTHFR in psychiatric diseases has important clinical implications, such as identification role of MTHFR and its genotypes in the psychiatric patients who respond or not respond to traditional pharmacological treatment for personalized treatment management of psychiatric diseases

Median complete local pain response rates ranged from 80% [16] to 100% [19], with median local pain-free survival rates reaching 76.8% (IQR 55.383.8) at the longest follow-up [16]

The Non-Responder Reports A meaningful subset of users reports little to no change