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10.1038/cddis.2015.51 16 BraultM.OberstA

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Systemic inflammatory mediators during the perioperative period can invade the brain and promote the neurotoxic A1 astrocyte phenotype, releasing a broad range of pro-inflammatory mediators that exacerbate neuroinflammation

Berberine is an isoquinoline alkaloid, of which the reports on NAFLD are abundant and suggest that berberine is a promising candidate for treatment on NAFLD