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Molecular interactions that enable movement of the Lyme disease agent from the tick gut into the hemolymph

TT: Writing original draft

Koklesova L, Mazurakova A, Samec M, Biringer K, Samuel SM, Bsselberg D, Kubatka P, Golubnitschaja O (2021) Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person

Mitochondrial oxidants play an essential role in disulfide bond formation, as inhibitors of mitochondrial oxidant production dramatically decrease overall levels of cellular disulfide bonds in many cells, including Chang liver cells and bovine aortic endothelial cells, whereas other oxidant-generating cellular enzymes (such as NOXs) do not affect these pathways (400)