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Interim results from a phase 1/2 clinical trial of AAV-based GRN gene therapy (PR006) have demonstrated that one-time injection of PR006 into the cisterna magna is generally safe and well tolerated and increases CSF PGRN levels [216]

If you or someone you know accidentally ingests too much acetaminophen, talk to a healthcare provider to see if NAC could be an appropriate course of treatment

[DOI] [PubMed] [Google Scholar] [182].Comini MA, Guerrero SA, Haile S, Menge U, Lunsdorf H, Flohe L, Validation of Trypanosoma brucei trypanothione synthetase as drug target, Free Radic

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