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DOI:10.1007/s00726-017-2447-9 [Google Scholar] Soda K

In resting cells, this effect is mediated by 2 -ARs, while in activated microglia, it involves 2A -ARs (88)

And that's where timing becomes critical

She et al., reported a neuroprotective effect of amygdalin together with two other glycosides (paeoniflorin and astragaloside IV) in a rat model of cerebral ischemia