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The Role of Metformin Recently metformin, a drug typically utilized for the management of blood glucose control in patients with type II diabetes, has come under evaluation as a potential pharmacological agent for the attenuation of aging

-L-glutamyl-L-cysteinylglycine) is a tripeptide involved in the scavenging of hydroxyl radical (*OH) and singlet oxygen, the reduction of H 2 O 2 , and for cellular detoxification through GSH- S -transferases

This process liberates a large amount of Hb and heme, causing pain crises in SCD patients (Kato et al., 2018

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