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In health cells, cytosolic NADH is shuttled into mitochondria, where it is turned into NAD + by OXPHOS whereas in cancer cells, the conversion of NAD + to NADH in mitochondria is not sufficient for the high rate of glycolysis due to reduced OXPHOS

This was contrary to the objective of the New Technology APC payment policy, which is to gather sufficient claims data to enable us to assign the service to an appropriate clinical APC