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doi:10.1016/j.ejphar.2017.05.032 Mehta R, Dedina L, OBrien PJ

While carpal tunnel may not be curable, it can often be managed effectively with the right approach

As a serine/threonine kinase, GSK3 has a strong preference for substrates harboring a S/TXXXS/T motif (X, any amino acid), which is usually primed as a target for GSK3 by phosphorylation of a residue four or five amino acids to the C-terminal side of the motif 12