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In addition to localization to basement membranes reported previously, GPX3 can be expressed by lung fibroblasts and associate with interstitial fibrotic ECM, suggesting a protective anti-oxidant function in this compartment

Lim JC, Arredondo C, Braakhuis M, A

M.GirardetJ.-M.DidierjeanC.et al (2016)

DNA methylation can also influence transcription of genes through methyl binding domain proteins (MBDs).18 MBDs recruit histone-modifying and chromatin-remodelling complexes to methylated sites, thereby forming compact, inactive heterochromatin