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(2019) found that inhibiting canonical Wnt signal transduction in bone marrow stromal cells prevented the development of MDS and proposed that activation of -catenin signalling in the bone marrow of MDS patients may be a new treatment strategy that reduces -catenin levels or inhibits Wnt/-catenin signalling

income received is donated to EEs institution for diabetes research

10.1038/s41569-018-0030-z Summary Keywords D-Gal, endothelial cell senescence, FOXO4-DRI, P53, ROS Citation Hu Z, Li F, Hu C, Shan Q, Tang Z, Jiang M, Yi X, Chen X, Jin L, Wang X and Wang Y (2026) FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway