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This increase in fat processing requires a steady supply of glutathione to prevent clogging the livers detoxification pathways

Biosens Bioelectron 179(1):113052 Meca AD, Turcu-Stiolica A, Stanciulescu EC, Andrei AM, Nitu FM, Banita IM, Matei M, Pisoschi CG (2021) Variations of serum oxidative stress biomarkers under first-line antituberculosis treatment: A pilot study

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Glutathione reductase (GR) can use NADPH to catalyze the reduction of oxidized glutathione (GSSG) to GSH, eliminating LPO on the cell membrane and preventing cell membrane damage, thereby inhibiting ferroptosis (Yang et al., 2014)