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Can You Take Vitamin B12 Supplements With Metformin? InternationalDrugMart If you have been on Metformin for several years, monitoring is essential. The B12 Link: Long term use (typically 4+ years) can interfere with Vitamin B12 absorption. Symptoms to Watch: Fatigue, memory issues Metformin use and vitamin B12 deficiency: New MHRA guidance DiabetesontheNet Metformin and B12 Deficiency Diabetes Self Management
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