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5,121 No studies have reported quantitatively on the benefit of sleep disorder management in populations with psychiatric conditions, but given the high psychosocial burden of idiopathic hypersomnia, it can be hypothesized that effective management of idiopathic hypersomnia (eg, improved functioning, daytime sleepiness, or sleep inertia) may positively impact psychiatric symptoms either directly or indirectly

Some of the effects may be tumor cell intrinsic, as reported for bladder cancer cells, in which AR targeting results in PDL1 suppression 37 , thereby enhancing natural killer (NK) cell activity and tumor suppression 128