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Although vitamin B12 deficiencies are relatively rare in people who consume enough animal products, vegans, vegetarians and people with certain digestive problems (such as stomach problems that affect B12 absorption) may develop a deficiency

Supplements take a minimum of 60 days before becoming effective where as a B12 shot works instantly

However, as with any injection, some individuals may experience mild side effects: Injection site reactions: Mild soreness, redness, or swelling at the injection site is the most common side effect

Thalamic neuronal dysfunction and chronic sensorimotor distal symmetrical polyneuropathy in patients with type 1 diabetes mellitus