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A study from the genomics and transcriptomics on Rhodococcus species suggests that 4-nitrophenol breaks down into acetyl-coA and succinate by nitrocatechol through Nph -specific genes (Miglani et al., could potentially facilitate effective detoxification of such undesirable metabolites and reduced accumulation of environmental contaminants, thus reducing biological and physiological complications

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1c,d) and was previously suggested as a candidate for a potential activator site, first, because its positive charge might stabilize or bind GSH as GS , and, second, because of its evolutionary conserved position that is equivalent to the GSH-interacting catalytic residue of glutathione transferases 3