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Lipid peroxides released early during ferroptosis act as damage-associated molecular patterns (DAMPs), promoting dendritic cell (DC) maturation and antigen cross-presentation, which in turn primes CD8 + T cells and enhances anti-tumor immunity ( + T cells and DCs, thereby positioning CDH4 as a promising target for combination therapies leveraging ferroptosis and immunotherapy

Cyanocobalamin (B12) restores mitochondrial energy production in deficient individuals, which can improve exercise tolerance and basal metabolic rate by 58%

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or p.o., alongside local lidocaine, and found the local B12 injection to be significantly more effective in pain relief than either i.m