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Interestingly, Bottari and colleagues reported even higher circulating markers of oxidation (MDA and AOPP) after CHOP chemotherapy (cyclophosphamide, vincristine, doxorubicin, and prednisone) in dogs with multicentric lymphoma, suggesting that the treatment might exacerbate OS levels [74]

This transformation happens primarily in the liver through a process called conjugation

Although coffee is often claimed to increase glutathione levels and GST activity, positive effects were only found in animals and cells

[PubMed] [Google Scholar] 44.Cerrahoglu K, Kunter E, Isitmangil T, Oztosun AI, Isitmangil G, Okutan O, et al