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The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress

Betz RC, Petukhova L, Ripke S, Huang H, Menelaou A, Redler S, Becker T, Heilmann S, Yamany T, Duvic M, Hordinsky M, Norris D, Price VH, Mackay-Wiggan J, de Jong A, DeStefano GM, Moebus S, Bhm M, Blume-Peytavi U, Wolff H, Lutz G, Kruse R, Bian L, Amos CI, Lee A, Gregersen PK, Blaumeiser B, Altshuler D, Clynes R, de Bakker PIW, Nthen MM, Daly MJ, Christiano AM (2015) Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci

Autophagy is a natural, regulated PCD behavior