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cabozantinib) have been used in most studies where combination therapy has been effective in tumors other than NSCLC, and there has been a lack of clinical attempts with selective MET-TKIs in combination with PD-1/PD-L1 inhibitors for other tumors

Their structures are often short chains, which makes them unstable

For instance, pairing a peptide that activates glutathione-associated pathways with one that stabilizes mitochondrial membranes can both reduce ROS generation and accelerate repair