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The influence of HCC metabolic reprogramming on immune effector cells CD8 + T cells Intratumoral glucose deprivation caused by dominant tumor glycolysis constrains glycolytic flux in activated CD8 + T cells

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Though several investigations have shown that EGCG and other catechins in green tea augment the activity of antioxidant enzymes and reduce oxidative stress markers and inflammatory markers (Reference Ye, Ye and Xu19Reference Bogdanski, Suliburska and Szulinska22) , there are equivocal effects on markers of oxidative stress, and inflammation in diabetes, metabolic syndrome, -thalassemia major, and obesity (Reference Lasaite, Spadiene and Savickiene15,Reference Azizbeigi, Stannard and Atashak23Reference Basu, Du and Sanchez28)

Induction of cell cycle arrest by the endogenous product of lipid peroxidation, malondialdehyde