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Description

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This neuroimmune-tumor connection is also paradoxical as links also exists between chronic inflammation and tumorigenesis, with glioma cells producing pro-inflammatory cytokines, chemokines, and growth factors that create an inflammation-enriched TME (65, 66)

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After overnight incubation, flow cytometry revealed pSTAT5 activation in CD4, CD8, and CD56 cells only upon MMP7 treatment (Fig

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