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For instance, EcN-MT [196], constructed by anchoring metallothionein on the bacterial surface through surface display technology, not only reduces the liver cadmium content in a cadmium-exposed mouse model but also improves liver steatosis, inflammatory infiltration, and fibrosis symptoms by activating the Nrf2-Keap1 pathway

We also review several recently completed trials and draw lessons that should be applied in future

FK506 enhances regeneration of axons across long peripheral nerve gaps repaired with collagen guides seeded with allogeneic Schwann cells