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Etwel, F., Faught, L

If this mutation takes place in critical region of an oncogene or tumor suppressor gene, it can lead to cancer

The role of the glutathione pathway in cellular defense against oxidative stress, particularly in environments compromised by surgical trauma and ischemia, has been substantiated through the upregulation of key enzymes such as GCLC, GPXs, GSR, and GSTs during the early phases of graft healing 14