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Discussion At present, clinical remedy of patients with chronic hepatitis B is mainly on the foundation of regular antiviral treatment, which can improve the patients liver function to a certain extent, turn HBV-DNA negative, delay the process of liver fibrosis, and has a definite impact on ameliorating the patients quality of life and survival rate

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Curr Mol Med 13(4):514534 McBrayer SK, Mayers JR, DiNatale GJ et al (2018) Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma