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Journal of Toxicology , 2012

Central sensitization refers to a phenomenon in which the central nervous system becomes hypersensitive to pain signals, leading to the perception of pain even without a noxious stimulus 8,9

Since ASD behavior depended on neurodevelopment in the regression models above as well in our previous studies [40, 41], a relationship between neurodevelopment and behavior was considered in the models and was found to be significant in every model