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Journal of Clinical Endocrinology & Metabolism

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Impairment of Fertility Two fertility studies conducted in adult rats at doses of up to 7.5 and 12.5 mg/kg/day (approximately 0.97 and 1.6 times, respectively, the MRHD of 60 mg given to adolescents on a mg/m2 basis) indicated that fluoxetine had no adverse effects on fertility

In certain embodiments, the pharmaceutical composition for oral administration provided herein is about 1.9 grams or less, about 1.8 grams or less, about 1.7 grams or less, about 1.6 grams or less, about 1.5 grams or less, about 1.4 grams or less, about 1.3 grams or less, It may be about 1.2 grams or less, 1 about 1.1 grams or less, about 1 gram or less, about 0.9 gram or less, about 0.8 gram or less, about 0.7 gram or less, about 0.6 gram or less, or about 0.5 gram or less