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RIPK1, a key FRG, has also been shown to be part of the same protein interaction network as immune checkpoints like PD-1 [239]

Samples were analysed in triplicate and read at 554 nm

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3309-A CLINICAL CHARACTERIZATION OF PATIENTS WITH WILSONS DISEASE AT LEIPZIG UNIVERSITY MEDICAL CENTER Magdalena Hahn 1 , Johannes Wiegand 1 , Madlen Matz-Soja 1 , Maja Schirmer 1 and Thomas Berg 2 , (1)Division of Hepatology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany, (2)University Hospital of Leipzig Background: Wilsons disease (WD) is rare and patients are referred to tertiary centers for treatment