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On this basis and considering that brain organoids are 3D cytoarchitectures resembling the embryonic human brain, many researchers and companies are developing protocols and pipelines for the generation, maintenance and analysis of brain organoids to model neurodevelopmental diseases (Lee et al., 2017

2007]Relationship between nocturnal growth hormone concentrations, serum IGF-I/IGFBP-3 levels, insulin sensitivity and GH receptor allelic variant in small for gestational age children