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The Lancet Oncol

Eichenlaub-Ritter, U

reported that fructose-1,6-bisphosphatase 2 (FBP2) expression is upregulated in brain metastasized cells of breast cancer origin to sustain and promote cancer cell survival by enhancing gluconeogenesis, as the absence of FBP2 compromises the proliferation and survival of these cells [66]