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Specifically, it upregulates genes involved in collagen synthesis (Types I, III, and V), decorin production (which regulates collagen fibril assembly), integrin and glycosaminoglycan synthesis, DNA repair enzymes, antioxidant defense systems (superoxide dismutase, glutathione), and stem cell markers

This results in the transition of copper ions between oxidized and reduced states, generating OH , which are considered the most powerful oxidizing radicals in biological systems and extremely reactive with biological molecules, at a substantial rate [38]

Emerging roles of astrocytes in neural circuit development