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High blood glucose levels can trigger oxidative stress (OS), a state of imbalance between oxidation and the antioxidant defence system in the body []

(b) This was also true for selenium and vitamin C in a single-blind RCT from India, the report of which gave no diagnostic criteria, stated gall stones / common bile duct stones as the commonest aetiological factor, did not specify if these problems were on-going, and administered proton pump inhibitors plus pancreatic extracts - both with antioxidant potential - to treatment and no-treatment groups (78)

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Depending on the hypotheses being studied, a number of epidemiological research strategies are available