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Description

FBXL5-null mice exhibit early embryonic lethality due to iron-induced oxidative stress, which can be prevented by the additional knockout (KO) of IRP2 17

Ashkenazi A, Dixit VM

Across tissues, FATP15 and CD36 are the transporters most consistently discussed in relation to IR/T2DM phenotypes, whereas FATP6 is primarily emphasized in cardiometabolic contexts