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L-asparaginase associated with high ASNS expression may be overcome by the use of ASNS inhibitor as reported in an in vitro study of L-asparaginase resistance leukemia cell line [89]

There is some indication that VDR polymorphisms modulate especially the risk for prostate, breast, colorectal and skin cancer ( 2.2

Enzyme-responsive drug delivery system has been demonstrated, which consist of triblock N-(2-hydroxypropyl methyl) acrylamide (HPMA) conjugated with tetrapeptide linker, which allows the high molecular weight (92 kDa) to degrade into low molecular weight (44 kDa) and deliver the paclitaxel drug at tumor site [54]

An analysis of the rhizome or root extracts of ginger plants using thin-layer chromatography confirmed that the curcumin content in different plants of the same genus and even in rhizomes and roots of the same plant are significantly different (Jianmin et al., 1983)