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An emerging technique known as direct optical lithography eliminates the need for polymer photoresists through photochemical reactions with surface ligands or additives to modify the nanomaterial films solubility, thereby reducing cost and environmental impact, achieving excellent resolution across a range of photon energies and wider material applicability [41]

Also nasal spray devices are typically 12.0 units per spray (125uL) The solution to get that into 4 sprays containing 20mg per spray (1 dose) = 80mg delivered would be a 16% concentration

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