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J Bone Miner Res 24:15311536

A recent publication provided the first evidence that catecholamines can induce the rearrangement of cellular cortical actin in human granulocytes, thereby decreasing cell stiffness and leading to leukocyte demargination ( in vitro increases interleukin-8 (IL-8) expression and CD11b (alpha-M-integrin) levels in human neutrophils ( in vitro stimulation with the adrenergic agents adrenaline, noradrenaline, or the agonist isoproterenol reduced N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced human polymorphonuclear cell (PMN) migration, CD11b/CD18 (Mac-1) integrin expression, as well as production of reactive oxygen species, without affecting IL-8 levels ( In addition to their direct influence on the leukocyte adhesion cascade, catecholamines also modulate functions of macrophages, a resident leukocyte subset

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The simple form of gastroschisis is characterized by the presence of an isolated defect, usually without visceroabdominal disproportion (up to 80%)a discrepancy between the volume of visceral organs and the conditional volume of the abdominal cavity, formed when the defect is closed without additional plastic interventions ( The complicated form of gastroschisis is characterized by the presence of combined malformations and prenatal complications